An internationally-recognized expert in the mechanisms of neurodegenerative diseases, Dr. Dale Bredesen’s career has been guided by a simple idea: that Alzheimer’s as we know it is not just preventable, but reversible. Thanks to a dedicated pursuit of finding the science that makes this a reality, his idea has placed Dr. Bredesen at the vanguard of neurological research, and led to the discoveries that today underlie the ReCode Report.
Dr. Bredesen earned his MD from Duke University Medical Center and served as Chief Resident in Neurology at the University of California, San Francisco (UCSF) before joining Nobel laureate Stanley Prusiner’s laboratory at UCSF as an NIH Postdoctoral Fellow. He held faculty positions at UCSF, UCLA and the University of California, San Diego. Dr. Bredesen also directed the Program on Aging at the Burnham Institute before joining the Buck Institute in 1998 as founding President and CEO.
Dr. Bredesen’s research explores previously uncharted territory in explaining the physical mechanism behind the erosion of memory seen in Alzheimer’s disease, and has opened the door to new approaches to treatment. This work has led to the identification of several new therapeutic processes that are showing remarkable early results.
Dr. Bredesen is a prodigious innovator in medicine, with over thirty patents to his name. Notably, he put much of his finding and research into the 2017 New York Times best-seller The End of Alzheimer’s.
In this paradigm shifting book, Dr. Bredesen offers real hope to anyone looking to prevent and even reverse Alzheimer's disease and cognitive decline.
Taking insights gleaned from over 40 years in medicine, Dr. Bredesen has authored a groundbreaking guide to prevent and reverse Alzheimer’s Disease that fundamentally changes how we understand cognitive decline.
Revealing that Alzheimer’s disease is not one condition, as it is currently treated, but rather three distinct conditions, The End of Alzheimer’s outlines 36 metabolic factors (micronutrients, hormone levels, sleep) that can trigger "downsizing" in the brain. The protocol shows us how to rebalance these factors using lifestyle modifications. It’s the perfect primer for educating yourself on what your ReCode Report will reveal.
The End Of Alzheimer's - Taking insights gleaned from over 40 years in medicine, Dr. Bredesen has authored a groundbreaking guide to prevent and reverse Alzheimer’s Disease that fundamentally changes how we understand cognitive decline.
Reversal of Cognitive Decline: 100 Patients Report of 100 patients, treated by several different physicians, with documented improvement in cognition, in some cases with documentation of improvement in electrophysiology or imaging, as well. This additional report provides further support for a randomized, controlled clinical trial of the protocol and the overall approach.
Reversal of cognitive decline in Alzheimer's disease. - The first description of the reversal of cognitive decline in patients with early Alzheimer's disease or its precursors, MCI (mild cognitive impairment) and SCI (subjective cognitive impairment).
Transcriptional Effects of ApoE4: Relevance to Alzheimer's Disease. - We showed that ApoE4 acts as a transcription factor and binds to the promoters of genes involved in a range of processes linked to aging and AD disease pathogenesis. These findings point to novel therapeutic strategies for AD and aging, resulting in an extension of human healthspan, the disease-free and functional period of life.